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Allderm Inc. 5213 Woodland Bay - Belmont, NC, 28012 - USA
(704) 825 5709 [email protected]

Skin is alive – different at every age.
The right choice decides

WHAT?

WHEN?

WHY?

SCIENCE

Cutitop®
Generation 1

1.69 oz.
liquid Cream

Adolescent skin without acne tendency to protect against the consequences of stress, sleep deficit, air pollution, etc.

0.05% biotin supports the stimulation of the formation of the top layer of the skin 1)

Hyaluronic acid stabilizes the youthful elasticity and elasticity of the skin 2)

Antioxidants reduce the number of free radicals that can cause cell damage and thus early skin aging 3)

1) https://lpi.oregonstate.edu/ mic/vitamins/biotinfunction

2) Bukhari SNA et al. Int J Biol Macromol. 2018 Dec;120(Pt B):1682-1695. doi: 10.1016/j.ijbiomac.2018.09.188. Epub 2018 Oct 1. Hyaluronic acid, a promising skin rejuvenating biomedicine

3) Dr. Bonnefoy M et al. Antioxydants to slow aging, Presse Med. 2002 Jul 27;31(25):1174-84.

WHAT?

WHEN?

WHY?

SCIENCE

Cutitop®
Generation 2

1.69 oz. Cream

First signs of skin dryness, such as slightly tense, rough or irritated skin.

0.10% biotin supports keratin formation and thus provides building blocks for the formation of the top layer of the skin 1)

Hyaluronic acid is equivalent to the moisture content of the skin from 2 years of age 2)

Antioxidants to protect against free radi-cals that can accelerate skin aging 3)

Phytosterol accelerates skin regeneration and improves its elasticity 4)

1) Dr. Jane Fore, Skin and the Effects of Aging on Skin Structure and Function, ISSN: 0889-5899 – Volume 52 – Issue 9 2006 – Pages: 24 – 35

2) Dr. Arianna Fallacara, Hyaluronic Acid in the Third Millennium, Polymers 2018, 10, 701; doi:10.3390/polym10070701

3) Dr. Ruta Ganceviciene et al., Skin anti-aging strategies, Dermatoendocri-nolv.4(3); 2012 Jul 1PMC3583892

4) Monika Michalak et al. Nut Oils and their Dietetic and Cosmetic Significance: a Review, Journal of Oleo Science, doi : 10.5650/jos.ess18216 J. Oleo Sci. 68, (2) 111-120 (2019)

WHAT?

WHEN?

WHY?

SCIENCE

Cutitop®
Generation 3

1.69 oz. Cream

Age spots, fine wrinkles, dry skin with loss

0.25% biotin eliminates fine wrinkles and reduces deep wrinkles by affecting the base substance, as well as the elastic and collagen fibers. 1)

5% Sophora flavescens brightens age spots in a targeted and clear way, reduces hyperpigmentation. 2)

3% Acmella Oleracea supports the smoothing of those fine wrinkles caused by the thousands of mini contractions of the facial muscles every day (expression wrinkles), with an injection-like effect that has a relaxing effect on the muscles.3)

Antioxidants provide protection against free radicals. 4)

1) Prof. Dr. med G. Floersheim, Influence of Topically Applied Biotin on Fine Wrinkles in the Skin of Elderly Patients, Dermatologisches 4/95 mc-Verlag


2)
Dr. Dae Hyun Shin, Whitening effect of Sophora flavescens extract, ISSN: 1388-0209 (Print) 1744-5116 (Online) homepage: https://www.tandfonline.com/loi/iphb20

3) Dr. Orapin Wongsawatkul et al. Vasorelaxant and Antioxidant Activities of Spilanthes acmella Murr. Int J Mol Sci. 2008 Dec; 9(12): 2724–2744.

4) Dr. Bonnefoy M et al. Antioxydants to slow aging, Presse Med. 2002 Jul 27;31(25):1174-84.

WHAT?

WHEN?

WHY?

SCIENCE

Cutipro®
Generation 1

combination pack: 50 ml liquid Cream Cutitop® Generation 1 plus 28 Capsules Cuticaps®

Visibly stressed, youthful skin without acne inclination; e.g. smokers, UV radiation, air pollution.

0.05% biotin plus 50 μg of biotin orally stimulate skin renewal from inside and outside. 1)

Hyaluronic acid binds water in the deeper layers of the skin. 2)

 

Topically applied and oral antioxidants trap free radicals in the body and on the skin, they provide protection and reduce the risk of early aging of the skin due to cell damage. 3)

1) McCusker et al., Nutrition and skin: Kids are not just little people. Clin Dermatol. 2016 Nov – Dec;34(6):698-709. doi: 10.1016/j.clindermatol.2016.07.004. Epub 2016 Jul 9.

2) Poetschke J. et al. Anti-wrinkle creams with hyaluronic acid: how effective are they?
MMW Fortschr Med. 2016 May 25;158 Suppl 4:1-6. doi: 10.1007/s15006-016-8302-1. Epub 2016 May 25.

3) Palmer DM et al, Oxidative damage, skin aging, antioxidants and a novel antioxidant rating system. J Drugs Dermatol. 2010 Jan;9(1):11-5.

WHAT?

WHEN?

WHY?

SCIENCE

Cutipro®
Generation 2

combination pack: 50 ml Cream Cutitop® Generation 2 plus 28 Capsules Cuticaps®

First signs of skin dryness, such as slightly tense, rough or irritated skin.

0.10% biotin topically plus 50 μg biotin orally support the keratin and neo-formation of the upper skin layer from inside and outside. 1)

Hyaluronic acid compensates for decreasing moisture content of the skin. 2)

Topical and oral antioxidants optimize protection against premature skin aging. 3)

1) MJanos Zempleni et al., Biotin, Biofactors. 2009 Jan-Feb; 35(1): 36–46. doi: 10.1002/biof.8

2) Pavicic T. et al,  Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. J Drugs Dermatol. 2011 Sep;10(9):990-1000.

2) Brown TJ, et al., Absorption of hyaluronan applied to the surface of intact skin, J Invest Dermatol. 1999 Nov;113(5):740-6.

3) Dr. Bonnefoy M et al. Antioxydants to slow aging, Presse Med. 2002 Jul 27;31(25):1174-84.

WHAT?

WHEN?

WHY?

SCIENCE

Cutipro®
Generation 3

combination pack: 50 ml Cream Cutitop® Generation 3 plus 28 Capsules Cuticaps®

Age spots, fine wrinkles, dry skin with loss of elasticity, rough and pale-looking skin

0.25% biotin topically plus 50 μg biotin orally accelerates keratin formation, eliminates fine wrinkles and reduces deep wrinkles by affecting the base substance, as well as the elastic and collagen fibers 1)

5% Sophora flavescens specifically and clearly brightens age spots, reduces hyperpigmentation, 2)

3% Acmella Oleracea supports the wrinkle-reducing effect of biotin with a spontaneous, injection-like effect. 3)

Topical and oral antioxidants optimize protection against premature skin aging. 4)

1) Prof. Dr. med G. Floersheim, Influence of Topically Applied Biotin on Fine Wrinkles in the  Skin of Elderly Patients,Dermatologisches 4/95 mc-Verlag

2) Dr. Dae Hyun Shin, Whitening effect of Sophora flavescens extract, ISSN: 1388-0209 (Print) 1744-5116 (Online) homepage: https://www.tandfonline.com/loi/iphb20

3) Dr. Orapin Wongsawatkul et al. Vasorelaxant and Antioxidant Activities of Spilanthes acmella Murr. Int J Mol Sci. 2008 Dec; 9(12): 2724–2744.

4) Silas Arandas Monteiro e Silva et al., An overview about oxidation in clinical practice of skin aging. An Bras Dermatol. 2017 May-Jun; 92(3): 367–374. doi: 10.1590/abd1806-4841.20175481

WHAT?

WHEN?

WHY?

SCIENCE

Cutifixx® Repair

50 ml Cream

Distinct wrinkles, age spots, dry skin with a feeling of tension that is rough and tired.

0.25% biotin eliminates fine wrinkles and reduces deep wrinkles by influencing the base substance, as well as the elastic and collagen fibers. 1)

5% Acmella Oleracea is targeted in smoothing those wrinkles caused by thousands of mini contractions of the facial muscles every day (expression wrinkles) – the injection-like effect has a spontaneously relaxing influence on the muscles, which eliminates fine wrinkles and reduces deep wrinkles within a few days. 2)

3%Sophora flavescens help to brighten age spots and reduce hyperpigmentation. 3)

Topical and oral antioxidants optimize protection against premature aging of the skin. 4)

1) Prof. Dr. med G. Floersheim, Influence of Topically Applied Biotin on Fine Wrinkles in the  Skin of Elderly Patients, Dermatologisches 4/95 mc-Verlag

2) Dr. Dae Hyun Shin, Whitening effect of Sophora flavescens extract, ISSN: 1388-0209 (Print) 1744-5116 (Online) homepage: https://www.tandfonline.com/loi/iphb20

3) Dr. Orapin Wongsawatkul et al. Vasorelaxant and Antioxidant Activities of Spilanthes acmella Murr. Int J Mol Sci. 2008 Dec; 9(12): 2724–2744.

WHAT?

WHEN?

WHY?

SCIENCE

Cutifixx® Repair plus

combination pack: 50 ml Cutifixx® Cream plus 28 Capsules Cuticaps®

Distinct wrinkles, age spots, dry skin with a feeling of tension that is rough and tired.

0.25% biotin topically plus 50 μg biotin orally accelerate keratin formation and skin renewal and eliminates fine wrinkles and reduces deep wrinkles due to internal and external effect that affects the base substance, as well as the elastic and collagen fibers. 1)

5% Acmella Oleracea is targeted in smoothing those wrinkles caused by thousands of mini contractions of the facial muscles every day (expression wrinkles) – the injection-like effect has a spontaneously relaxing influence on the muscle, whereby fine wrinkles are eliminated and deep wrinkles reduced within a few days. 2)

3%Sophora flavescens help to brighten age spots and reduce hyperpigmentation. 3)

Topical and oral antioxidants optimize protection against premature aging of the skin. 4)

1) Prof. Dr. med G. Floersheim, Influence of Topically Applied Biotin on Fine Wrinkles in the  Skin of Elderly Patients, Dermatologisches 4/95 mc-Verlag

2) Dr. Dae Hyun Shin, Whitening effect of Sophora flavescens extract, ISSN: 1388-0209 (Print) 1744-5116 (Online) homepage: https://www.tandfonline.com/loi/iphb20

3) Dr. Orapin Wongsawatkul et al. Vasorelaxant and Antioxidant Activities of Spilanthes acmella Murr. Int J Mol Sci. 2008 Dec; 9(12): 2724–2744.

4) Flavia Alvim Sant´anna Addor, Antioxydants in Dermatology, An. Bras. Dermatol. vol.92 no.3 Rio de Janeiro May/June 2017.

WHAT?

WHEN?

WHY?

SCIENCE

Cutiaid®

50 ml Cream

First signs of skin dryness, such as slightly tense, rough or irritated skin.

5% urea plus glycerin in a special base helps with a double effect on dry skin. 1)

The effect is spontaneous as the moisturizer becomes immediately felt and visible, also the absorption of topically applied biotin into deeper skin layers is significantly improved. 2)

1) Friedman AJ, et al., Urea: A Clinically Oriented Overview from Bench to Bedside, J Drugs Dermatol. 2016 May 1;15(5):633-9

2) Celleno L, Topical urea in skincare: A review, Dermatol Ther. 2018 Nov;31(6):e12690. doi: 10.1111/dth.12690. Epub 2018 Oct 30

WHAT?

WHEN?

WHY?

SCIENCE

Cuticaps®

Skin-specific food supplements

with a combination of micronutrients and antioxidants essential for the skin.

Skin protection of smokers and increased exposure to sun, smog and environmental pollution.

Biotin supports the production of keratin in the specialized cells and thus accelerates skin renewal. 1)

Vitamins A and E eliminate free radicals, promote a positive free radical balance and thus protect against their destructive effects. 2)

Riboflavin is not available in the body and must therefore be supplied daily in order to develop its beneficial effect on cell division. 3)

Pantothenate prevents excessive fat formation on the skin and its consequences. 4)

Nicotin acidamide supports the breakdown of toxic substances that also lead to acne, for example. 5)

1) MJanos Zempleni et al., Biotin, Biofactors. 2009 Jan-Feb; 35(1): 36–46. doi: 10.1002/biof.8

2) Flavia Alvim Sant´anna Addor, Antioxydants in Dermatology, An. Bras. Dermatol. vol.92 no.3 Rio de Janeiro May/June 2017.

3) Dr. Bonnefoy M et al. Antioxydants to slow aging, Presse Med. 2002 Jul 27;31(25):1174-84.

4) Wiederholt T. et al, Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts, Exp Dermatol. 2009 Nov;18(11):969-78. doi: 10.1111/j.1600-0625.2009.00884.

5) Dr. Ruta Ganceviciene et al., Skin anti-aging strategies, Dermatoendocrinolv.4(3); 2012 Jul 1PMC3583892

WHAT?

WHEN?

WHY?

SCIENCE

Eyfit®

8 ml Cream

Fine wrinkles around eyes, swollen eyelids, bags, dark circles, tired-looking eye areas.

The decongestant effect of the extract of elderflower 1)

The stabilizing effect of Hyaluronic acid. 2)

The skin in the eye area, which is prone to sagging, is tightened and strengthened by the strong wrinkle-reducing effect of the palmite oil. Swollen eyelids, bags, wrinkles in the eye area are permanently reduced. 3)

1) Cavero RY et al., Medicinal plants used for dermatological affections in Navarra and their pharmacological validation, J Ethnopharmacol. 2013 Sep 16;149(2):533-42. doi: 10.1016/j.jep.2013.07.012

 2) Pavicic T. et al.,  Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. J Drugs Dermatol. 2011 Sep;10(9):990-1000.

3) Kim HM, et al., Effects of palmitoil-KVK-L-ascorbic acid on skin wrinkles and pigmentation, Arch Dermatol Res. 2017 Jul;309(5):397-402. doi: 10.1007/s00403-017-1731-6